Dominik R Bach

Dominik R Bach

Prof. Dominik R. Bach, MD, PhD
University of Zurich: Assistant Professor for Psychiatric Research and Consultant (Oberarzt) in anxiety/affective disorders
University College London: Honorary Research Fellow of the Wellcome Trust Centre for Neuroimaging

Education
2002: Dipl.-Psych. (MSc) in Psychology, Technical University Berlin
2005: Dr. med., Charité Medical School, HU Berlin
2008: Dr. phil. (PhD), Institute of Psychology, TU Berlin
2012: Board certification in Psychiatry (Facharzt), Ärztekammer Berlin
2014: BSc Maths, Open University, Milton Keynes UK

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Key papers:

Bach DR, Tzovara A, Vunder J (2017). Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline. Molecular Psychiatry, in pressPDF

Korn CK, Vunder J, Miro J, Fuentemilla L, Hurlemann R, Bach DR (2017). Amygdala lesions reduce anxiety-like behavior in a human benzodiazepine-sensitive approach-avoidance conflict test. Biological Psychiatryin pressPDF

Bach DR, Symmonds M, Barnes G, Dolan RJ (2017). Whole-brain neural dynamics of probabilistic reward prediction. Journal of Neuroscience, 37, 3789-3798. PDF

Bach DR (2015). Anxiety-like behavioural inhibition is normative under environmental threat-reward correlations. PLOS Computational Biology, 11, e1004646. PDF

Bach DR, Guitart-Masip M, Packard PA, Miró J, Falip M, Fuentemilla L, Dolan RJ (2014). Human hippocampus arbitrates approach-avoidance conflict. Current Biology, 24, 541-547. PDF

 

Key reviews

Bach DR, & Dayan, P (2017). Algorithms for survival: a comparative perspective on emotions. Nature Reviews Neuroscience, in pressPDF

Stephan KE, Bach DR, Fletcher PC, Flint J, Frank MJ, Friston KJ, Heinz A, Huys QJ, Owen MJ, Binder EB, Dayan P, Johnstone EC, Meyer-Lindenberg A, Montague PR, Schnyder U, Wang XJ, Breakspear M (2016). Charting the landscape of priority problems in psychiatry, part 1: classification and diagnosis. Lancet Psychiatry3, 77-83. PDF

 

Recent papers

2017

Bach DR, Tzovara A, Vunder J (2017). Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline. Molecular Psychiatry, in pressPDF

Bach DR, & Dayan, P (2017). Algorithms for survival: a comparative perspective on emotions. Nature Reviews Neuroscience, in pressPDF

Korn CK, Vunder J, Miro J, Fuentemilla L, Hurlemann R, Bach DR (2017). Amygdala lesions reduce anxiety-like behavior in a human benzodiazepine-sensitive approach-avoidance conflict test. Biological Psychiatryin pressPDF

Bach DR, Symmonds M, Barnes G, Dolan RJ (2017). Whole-brain neural dynamics of probabilistic reward prediction. Journal of Neuroscience, 37, 3789-3798. PDF

Korn CK, Staib M, Tzovara A, Castegnetti G, Bach DR (2017). A pupil size response model to assess fear learning. Psychophysiology, 54, 330-343. PDF

Castegnetti G, Tzovara A, Staib M, Gerster S, Bach DR (2017). Assessing fear learning via conditioned respiratory amplitude responses. Psychophysiology, 54, 215-223. PDF

Khemka S, Tzovara A, Gerster S, Quednow BB, Bach DR (2017). Modelling startle eye blink electromyogram to assess fear learning. Psychophysiology, 54, 202-214. PDF

Bach DR (2017). The cognitive architecture of anxiety-like behavioural inhibition. Journal of Experimental Psychology: Human Perception and Performance, 43,18-29. PDF

 

2016

Bach DR, Gerster S, Tzovara A, Castegnetti G (2016). A linear model for event-related respiration responses. Journal of Neuroscience Methods270, 174-155. PDF

Castegnetti G, Tzovara A, Staib M, Paulus PC, Hofer N, Bach DR (2016). Modelling fear-conditioned bradycardia in humans. Psychophysiology, 53, 930-939. PDF

Korn CW & Bach DR (2016). A solid frame for the window on cognition: Modelling event-related pupil responses. Journal of Vision, 16:28,1-6. PDF

Paulus PC, Castegnetti G, & Bach DR (2016). Modeling event-related heart period responses. Psychophysiology, 53, 837-846. PDF

2015

Bach DR (2015). Anxiety-like behavioural inhibition is normative under environmental threat-reward correlations. PLOS Computational Biology, 11, e1004646. PDF

 Korn CW & Bach DR (2015). Maintaining Homeostasis by Decision-Making. PLOS Computational Biology, 11, e1004301. PDF

Bach DR, Hurlemann R, Dolan RJ (2015). Impaired threat prioritisation after selective bilateral amygdala lesions. Cortex, 63, 206-213. PDF

Bach DR (2015). A cost minimisation and Bayesian inference model predicts startle reflex modulation across species. Journal of Theoretical Biology, 370, 53-60.  PDF

Bach DR, Staib M (2015). A matching pursuit algorithm for inferring tonic sympathetic arousal from spontaneous skin conductance fluctuations. Psychophysiology, 52, 1106-12. PDF

Bach DR, Furl N, Barnes G, Dolan RJ (2015). Sustained Magnetic Responses in Temporal Cortex Reflect Instantaneous Significance of Approaching and Receding Sounds. . PLOS ONE, 10, e0134060. PDF

Bach DR, Seifritz E, Dolan RJ (2015). Temporally unpredictable sounds exert a context-dependent influence on evaluation of unrelated images. PLOS ONE, 10, e0131065. PDF

Staib M, Castegnetti G, Bach DR (2015). Optimising a model-based approach to inferring fear learning from skin conductance responses. Journal of Neuroscience Methods, 255, 131-138. PDF

2014

Bach DR, Guitart-Masip M, Packard PA, Miró J, Falip M, Fuentemilla L, Dolan RJ (2014). Human hippocampus arbitrates approach-avoidance conflict. Current Biology, 24, 541-547. PDF

Pooresmaeli A, FitzGerald THB, Bach DR, Toelch U, Ostendorf F, Dolan RJ (2014). Crossmodal effects of value on perceptual acuity and stimulus encoding. PNAS, 111, 15244-15429.

Bach DR, Schmidt-Daffy M, Dolan R (2014). Facial expression influences face identity recognition during the attentional blink. Emotion, 14, 1007-1013. PDF

Toelch U, Bach DR, Dolan RJ (2014). The neural underpinnings of an optimal exploitation of social information under uncertainty. Social Cognitive and Affective Neuroscience, 9, 1746-1753.

Bach DR (2014). A head-to-head comparison of SCRalyze and Ledalab, two model-based methods for skin conductance analysis. Biological Psychology, 103, 63-88. PDF

Bulganin L, Bach DR, Wittmann BC (2014). Prior fear conditioning and reward learning interact in fear and reward networks. Frontiers in Behavioral Neuroscience, 8, 67.

Pooresmaeili A, Bach DR, Dolan RJ (2014). The effect of visual salience on memory-based choices. Journal of Neurophysiology, 111, 481-487.

 2013

Bach DR, Friston KJ, Dolan RJ (2013). An improved algorithm for model-based analysis of evoked skin conductance responses. Biological Psychology, 94, 490-497. PDF

Bach DR, Hurlemann R, & Dolan RJ (2013). Unimpaired discrimination of fearful prosody after amygdala lesion. Neuropsychologia, 51, 2070-2074. PDF

2012

Bauer M, Kluge C, Bach D, Bradbury D, Heinze HJ, Dolan RJ, & Driver J (2012). Cholinergic enhancement of visual attention and neural oscillations in the human brain. Current Biology, 22, 397-402.

Campbell-Meiklejohn DK, Kanai R, Bahrami B, Bach DR, Dolan RJ, Roepstorff A, & Frith CD (2012). Structure of orbitofrontal cortex predicts social influence. Current Biology, 22, R123-R124.

Chumbley JR, Flandin G, Bach DR, Daunizeau J, Fehr E, Dolan RJ, & Friston KJ (2012). Learning and Generalization under Ambiguity: An fMRI Study. PLOS Computational Biology, 8 (1).

2011

Klein-Flügge MC, Hunt LT, Bach DR, Dolan RJ, & Behrens TEJ (2011). Dissociable Reward and Timing Signals in Human Midbrain and Ventral Striatum. Neuron, 72, 654-664.

Bach DR, Weiskopf N, & Dolan RJ (2011). A stable sparse fear memory trace in human amygala. Journal of Neuroscience, 31, 9383-9389.

Guitart-Masip M, Fuentemilla L, Bach DR, Huys QJM, Dayan P, Dolan RJ, & Duzel E (2011). Action dominates valence in anticipatory representations in the human striatum and dopaminergic midbrain. Journal of Neuroscience, 31, 7867-7875.

Bach DR, Talmi D, Hurlemann R, Patin A, & Dolan RJ (2011). Automatic relevance detection in the absence of a functional amygdala. Neuropsychologia, 49, 1302-1305.

Bach DR, Hulme O, Penny W, & Dolan RJ (2011). The known unknowns: Neural representation of second-order uncertainty, and ambiguity. Journal of Neuroscience, 31, 4811-4820.

 

Bach DR, Buxtorf K, Strik WK, Neuhoff JG, & Seifritz E (2011). Evidence for impaired sound intensity processing in schizophrenia. Schizophrenia Bulletin, 37, 426-431.

Bach DR, Behrens TE, Garrido L, Weiskopf N, Dolan RJ (2011). Deep and superficial amygdala nuclei projections revealed in vivo by probabilistic tractography. Journal of Neuroscience, 31, 618-23.

Bach DR, Daunizeau J, Kuelzow N, Friston KJ, & Dolan RJ (2011). Dynamic causal modelling of spontaneous fluctuations in skin conductance. Psychophysiology, 48, 252-57.